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Lab Projects

Current projects in the lab are associated with an NIH Pathway to Indepenence award titled: Role of novel CNS subcircuits in cue-induced drug relapse.

NIDA R00DA037271

To examine whether subregions within orbitofrontal-basolateral amygdala circuits may differentially affect relapse to cue-induced cocaine-seeking behavior, we will:

  • Map subregions of the orbitofrontal cortex (ventro, lateral, dorsolateral) that send monosynaptic projections to subregions of the basolateral amygdala (rostral, caudal).

  • Assess cue-induced neural activation in the above-mentioned subregions.

  • Use circuit-specific viral and optogenetic manipulations to potentially alter reinstatement of drug-seeking behavior.

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