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Lab Projects
Current projects in the lab are associated with an NIH Pathway to Indepenence award titled: Role of novel CNS subcircuits in cue-induced drug relapse.
NIDA R00DA037271
To examine whether subregions within orbitofrontal-basolateral amygdala circuits may differentially affect relapse to cue-induced cocaine-seeking behavior, we will:
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Map subregions of the orbitofrontal cortex (ventro, lateral, dorsolateral) that send monosynaptic projections to subregions of the basolateral amygdala (rostral, caudal).
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Assess cue-induced neural activation in the above-mentioned subregions.
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Use circuit-specific viral and optogenetic manipulations to potentially alter reinstatement of drug-seeking behavior.
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